Covid Vaccine thread

[nullnor]

the best case scenario for me is i think i've had covid twice. both times i got a runny nose and slight headache and i felt like my respiratory system was acting a little weird. it can also make you crazy. heh. that's a disturbing thought. one of the symptoms of long covid is insanity. also, i think long covid is simply the damage the virus has done. it's not hiding in your body. not that i would compare it to Havana syndrome, which i think doesn't exist. and that's a scary thought, our diplomats and higher officers think they are getting bombarded by cosmic rays. additionally, you know those double blind studies where more ppl in the placebo group quit because they think they are having side effects. i always thought Havana syndrome was the effect casino cigar conventions.

i've only been sick in my life like 2-3 times. mostly. i don't count colds, but i can't remember the last time i got one. the downside to that is i never get to miss a day of school or sick day at work. perfect attendance from 5th grade to 8th. and 10 years at my last job before i took a sick day. i feel like Bruce Willis in unbreakable. never broken a bone, never had a cavity. i know why too. i bet i was a vaginal birth instead of caesarian section. and then i was the dirtiest kid you ever saw. always around pets challenging my immune system. then as i got older i landscaped for a decade, always outside. and even during the last 20 years of changing into being an underground cave dweller, that immunity stayed with me.

the other day i asked my mother, how many times do you remember me being sick? she paused for a second and said never. that was a pretty cool moment.

[Sour Masher]

Nurse explains why she won’t get COVID-19 vaccine https://www.mailtribune.com/top-stor...id-19-vaccine/

this is probably the best explanation i've seen. for what it's worth.

She lost me here:

“God has me on this path, and he has a plan. I don’t understand it, but I’m going to do it,” she said.

How does she know who has what path and plan for her? Abdicating decision making by claiming a higher power has a plan is not a sound way to live one's life.

and then again here:

"Brown said people with underlying health problems should get vaccinated against COVID-19. But she said her healthy lifestyle and years of exposure to germs and viruses at the hospital have given her a strong immune system."

That is not how it works. COVID is a novel and highly contagious disease. Lots of healthy people have gotten it and while it does affects the elderly and immune-compromised much more, lots of younger, healthy people have died of it.


And again here:

"Brown said she’s not willing to get injected with COVID-19 vaccines because they use technology that is new for vaccinations."

1. RNA tech is not new, and J and J doesn't use it.

[nullnor]

netflix could make a new dystopian TV series where in the future having a strong immune system is a crime.

[Sour Masher]

netflix could make a new dystopian TV series where in the future having a strong immune system is a crime.

Again, that is not how it works. COVID is a novel pathogen. It doesn't matter how much practice your immune system has had with old viruses. The first time you come in contact with COVID, you have no antibodies for it. It is like you have been defending against sword attacks with a suit of armor and get zapped by a taser. Your defense isn't going to work.

[nullnor]

She lost me here:

“God has me on this path, and he has a plan. I don’t understand it, but I’m going to do it,” she said.

and then again here:

"Brown said people with underlying health problems should get vaccinated against COVID-19. But she said her healthy lifestyle and years of exposure to germs and viruses at the hospital have given her a strong immune system."


And again here:

"Brown said she’s not willing to get injected with COVID-19 vaccines because they use technology that is new for vaccinations."

yeah the religious opening isn't the most effective start for the audience you are targeting. but it is true more exposure to microbes can give you stronger immune system. not sure that is a good look for a hospital though. also, it is a new technology. but it's been around for decades in theory, and has been refined and ready to use for a while. maybe what ppl mean by that is not being able to have long term safety trials. i guess it is a misnomer since so many different companies were able to pump the technology out. who knows, maybe it's been the safest emergency use in history. i have to remember to drop that reason, i think i did but forgot.

it's hard to explain. and that's true because there is no explanation because it's wrong and everyone should get vaccinated. one thing i have a hard time wrapping my mind around is if the vaccine protects ppl what are the other reasons for mandating it. it's still going to spread. or maybe i am being defeatist. so then being unvaxxed is like smoking debate, if people want to inadvertently kill themselves. but then you could be against smoking anyways.

i thought the medical freedom thing was a good idea. also, how many ppl are immune. the main goal is stopping transmission and i think vaccines help accomplish it. it lowers viral load and thus lowers transmission. then the elephant in the room is how many ppl are immune naturally and how long. i am one. that nurse thinks she's two. they think it's enough of a question to do a global genetic study on it. there's probably a sequencing hub near everyone. there's one near me.

[nullnor]

Again, that is not how it works. COVID is a novel pathogen. It doesn't matter how much practice your immune system has had with old viruses. The first time you come in contact with COVID, you have no antibodies for it. It is like you have been defending against sword attacks with a suit of armor and get zapped by a taser. Your defense isn't going to work.

might not be true. your immune system is like predicting weather. it works in small samples but when you try to get the overall system it's chaos theory. some ppl have immunity. there is always someone with immunity to anything. but nature always wins. this virus is related enough to common colds they say. your first line of defense is your nose. mucosal immunity. nasal microenvironment? once the virus makes it though that then the real antibodies get involved. which ppl don't have. but it's not like Cortes 500 years ago bringing smallpox to Mexico.

the vaccines not having B-cell memory is a good question. there is a lot of upsides to that if it were true.

[nullnor]

off topic, did you know if you take a piece of your DNA and bring it across the room, supposedly you can make DNA contract and expand, supposedly even being scared or relaxed can do it. and then when you get scared, both DNA's contract. spooky action at a distance. quantum mechanics at a large biological coherent state. one wave function.

DNA expansion is cool. it determines what temperature it can survive at. the hottest record for a DNA based lifeform at 250F, but most lifeforms i think it's lower. DNA survives by packing it's proteins in closer. and there is an upper limit on carbon based DNA life for planets.

[nullnor]

you could be like Jon Stewart, hey nullnor it's a Novel Virus! it means it's new. fresh, original, nascent don't you know the meaning of new?

it appears the discussion has falling apart Sir when we encountered the meaning of new.

[nullnor]

The central role of the nasal microenvironment in the transmission, modulation, and clinical progression of SARS-CoV-2 infection https://www.nature.com/articles/s41385-020-00359-2
they even have a journal for Mucosal Immunology lol. they have a journal for everything.

There are two major types of nasal mucosal defenses. A physicochemical barrier is formed by the tightly bound ciliated, goblet, and basal epithelial cells, by the double mucus layer, and by the basement membrane. In addition, several extracellular molecules such as the beta-defensins and galectins show proinflammatory and antimicrobial properties...Pathogens can disrupt the mucus barrier by the production of several degradative enzymes, by exploiting the uptake by M cells or, when present, by the aid of a flagellum.

the basement membrane! anyone..anyone. the beta-defensins and galectins are in the basement membrane, playing cards talking about how to build a better physicochemical barrier. and then the virus goes over to any M cells it can find and says, hey buddy do me a favor and carry this enzyme over to the physicochemical not knowing that the thing is loaded.

i think there is a market for explaining immunology in terms of military history. comparing pathogens to enemy forces like Tim Pigott-Smith in the show Battlefield. 'and here we can see galectins launching pincer movements from north and south simultaneously even as the covid 19 encircled Stalingrad'.

[nullnor]

the M cells ride the flagellum like Targaryens riding dragons. after they receive the enzyme package they yell at the flagella 'Valahd” in Dothraki

[nullnor]

a lot of that paper is blah blah. but there's some good stuff.

"NALT (Nasopharynx-Associated Lymphoid Tissue) is underrepresented in germ-free mice compared with wild-type mice, suggesting that its development comes from the interaction with the microbiota after birth."

"Moreover, innate immune cell activation is based on a complex system of pattern recognition receptors (PRRs), that are able to recognize a large number of pathogen-associated molecular patterns, shared by an entire class of pathogens but not expressed on host cells."

it's a heuristic virus scanner. it's a novel virus but your own microbiota defenses wasn't born yesterday. when it comes to science, we make extraordinary strides but the fundamental rule is don't underestimate nature because given enough time it can always do it better. this rule also applies when defending zoonotic origin theory. everything is always possible. and even likely

[nullnor]

and then we come out with an unrelated poorly timed recommendation to not self medicate with aspirin if you don't have serious cardiovascular issues even when some studies show it has a 60% beneficial effect on ppl with covid. it's like they are trying to kill ppl.

this is what i call healthcare autopilot. similar to Hanlon's razor, it's where a guy like me brings my cat in for an $300 echocardiogram for heart enlargement each year for 3-4 years even though it's only a genetic disposition in maine coon cats and cats with poor taurine diets. and no-one bothered to check her blood pressure or test for hyperthyroidism. the cardiologist doesn't care, it's not his job, he's getting paid. it's not conscious, it's the vets job. the vet doesn't care, he's getting paid and he thinks it's the cardiologists job. but you know who's job it really is? it was my job.

[revo]

Nurse explains why she won’t get COVID-19 vaccine https://www.mailtribune.com/top-stor...id-19-vaccine/

this is probably the best explanation i've seen. for what it's worth.

Blah blah blah.

3.8 BILLION people in the world have received at least one dose of a covid vaccine, and 2.9 BILLION are fully vaccinated. In total, almost 7 BILLION shots have been administered -- over 45% of the entire population in the world have received at least one dose. Please, enough with the nonsense that this will cause horrendous side effects or it's not tested or you're a sheep or some other phony baloney.

Good luck to her in her new career as a janitor or working at McDonalds (although they may require the vaccine as well, LOL).

[The Feral Slasher]

Blah blah blah.

3.8 BILLION people in the world have received at least one dose of a covid vaccine, and 2.9 BILLION are fully vaccinated. In total, almost 7 BILLION shots have been administered -- over 45% of the entire population in the world have received at least one dose. Please, enough with the nonsense that this will cause horrendous side effects or it's not tested or you're a sheep or some other phony baloney.

Good luck to her in her new career as a janitor or working at McDonalds (although they may require the vaccine as well, LOL).

Yeah, instead of being internet sleuths people should just get advice from their doctor. Crazy idea, I know.

[nullnor]

i feel like Frank Costanza in the episode where he cooked. or that guy from the mail room. 'It's a hot night. The mind races. You think about your knife; the only friend who hasn't betrayed you, the only friend who won't be dead by sun up. Sleep tight, mates, in your quilted Chambray nightshirts.' i'm Eddie Sherman. i'm rattled. or the movie Airplane II, Striker was the squadron leader. he brought us in real low. but he couldn't handle it...Buddy couldn't handle it? was Buddy one of your crew? right. Buddy was the bombardier. but it was Striker who couldn't handle it, and he went to pieces. ..Over Macho Grande? No. I don't think I'll ever get over Macho Grande.