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one of my concerns about the vaccines was whether they can accidentally write to a persons DNA. I did a little searching and saw that scientists had anticipated this question and had addressed it last year. the Moderna and Pfizer, in theory, shouldn't be able to. in order for a virus to insert code in your DNA it has to be able to go into the nucleus of a cell. then it makes it's RNA and sends it to cytoplasm or something as instructions for the body to make antibodies. since the vaccine is already an RNA molecule, it doesn't go in the nucleus. there is an enzyme called transcriptase or something, which converts RNA into DNA but coronaviruses don't have this enzyme.
the other vaccines that use a more traditional approach, an inactivated virus carrying the instructions to make antibodies, supposedly use vectors to prevent it from accessing the nucleus. so I am assuming the chance is ultra low but not zero. the problem with writing to DNA is that you could accidentally knock out an important gene, like one that might be a tumor suppressing one. I think there is a company called Bluebird bio or something that recently had to suspend trials of something to investigate this.
I am a little surprised at the anti anti-vaxxers shouting down people that have questions about this stuff. if they understand the science I give them a pass. but if they don't or are not aware of the rare times there have been problems then they could be more helpful in explaining why these vaccines should be safe. for example, I didn't know that at first, some of the polio vaccines were infected with simian virus 40 (SV40) this is a type of virus, in theory, known to promote cancer. studies have been done, and they say the contamination didn't lead to higher incidents of cancer. also, if you go to the CDC's vaccination information center, they don't mention a dengue vaccine for children in the Philippines that cause ADE making recipients more susceptible to dengue.
actually the researching this stuff a little just made me want to someday get gene therapy to make my telomeres longer and live forever. what does it mean when they say they tested it on 'cancer resistant' mice? how do you make a mouse resistant to cancer, heh.
I started wondering that, there are so many fucking things in the environment now that can promote cancer. hey, science is wonderful right? until you start dumping chemicals in drinking water that last forever. I wonder if someday they'll be so many things, they won't be able to tell if something is specifically a culprit in cancer. because everyone will just be getting it. I guess by that time cancer will be cured.
I have two rules in life:
1) start with the idea, assume cats know everything.
2) assume humans know nothing.
the other vaccines that use a more traditional approach, an inactivated virus carrying the instructions to make antibodies, supposedly use vectors to prevent it from accessing the nucleus. so I am assuming the chance is ultra low but not zero. the problem with writing to DNA is that you could accidentally knock out an important gene, like one that might be a tumor suppressing one. I think there is a company called Bluebird bio or something that recently had to suspend trials of something to investigate this.
I am a little surprised at the anti anti-vaxxers shouting down people that have questions about this stuff. if they understand the science I give them a pass. but if they don't or are not aware of the rare times there have been problems then they could be more helpful in explaining why these vaccines should be safe. for example, I didn't know that at first, some of the polio vaccines were infected with simian virus 40 (SV40) this is a type of virus, in theory, known to promote cancer. studies have been done, and they say the contamination didn't lead to higher incidents of cancer. also, if you go to the CDC's vaccination information center, they don't mention a dengue vaccine for children in the Philippines that cause ADE making recipients more susceptible to dengue.
actually the researching this stuff a little just made me want to someday get gene therapy to make my telomeres longer and live forever. what does it mean when they say they tested it on 'cancer resistant' mice? how do you make a mouse resistant to cancer, heh.
I started wondering that, there are so many fucking things in the environment now that can promote cancer. hey, science is wonderful right? until you start dumping chemicals in drinking water that last forever. I wonder if someday they'll be so many things, they won't be able to tell if something is specifically a culprit in cancer. because everyone will just be getting it. I guess by that time cancer will be cured.
I have two rules in life:
1) start with the idea, assume cats know everything.
2) assume humans know nothing.
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